Season 1 of ASSIST ME! is actually a set of special videos within Maximillian's "Marvel Vs. Capcom 3: The Online Warrior" commentary series. Four characters are covered in the story arc: Doctor Doom, Albert Wesker, X-23 and Jill Valentine.
In this season, Doom becomes a recurring visitor to Max's apartment. They are antagonized by Wesker, who plans to gather combat data using Max's knowledge of Marvel Vs. Capcom 3, and use the data to spread the deadly Uroboros virus around the world. X-23 pursues Wesker, and visits Max and Doom as a result. Wesker also forces Max to "program" Jill in order to make her a more efficient weapon.