Season 2 covers four characters: Deadpool, Chris Redfield, Phoenix and Taskmaster. In this season, Doom's dreams are haunted by a dark and mysterious entity. M.O.D.O.K. hires Deadpool to kill Max and Doom, and they are surprised by help from Wesker. Taskmaster, working for the unknown enemy, unleashes the t-Virus in Santa Monica, causing a zombie outbreak, and allies himself with both M.O.D.O.K. and Deadpool against our heroes. Seeking guidance from Phoenix, the guys learn that their mysterious antagonist may be more than they can handle.