In the Christmas special, Max and Wesker made Rocket Raccoon drink a bottle of Doom Equis (Max believed that Rocket Raccoon was killed by drinking it).
In Part 1 of Chris Redfield's "Assist Me" Episode, it was on the TV before Doom noticed Chris Redfield and his teammates.
You can now pick up the official Dom Equis shirt at http://www.eightysixedclothing.com/maximilian/, Max's offcial partner!
Doom Equis Commercial (Transcript)EditNarrator: He runs a country, but still prefers a title of Doctor. He got a Ph.D. in the University of Phoenix, because he schooled that b*tch for free. All matchups are 9 to 1 in Doom's favor, even versus himself. He is the most interesting villain in the world!
Dr. Doom: I don't always use X-Factor, but when I do, I prefer the Finger Lazers! Stay salty, my friends!
- Doom Equis is an obvious parody of real-life lager Dos Equis. The commercial for the Doom Equis also parodies "The Most Interesting Man in the World" commercial for Dos Equis.